Phil -
Yes, an organic vapor cartridge and pre-filter is probably the right protection vs. mineral spirits. BUT -
1. Are you sure you have the right size for your face? A half-face respirator (which I presume is what you are using) has 3 sizes normally - S M L.
2. Are you clean-shaven in the area where the respirator mask makes contact with facial skin? As in no beard stubble.... A half-face respirator depends on an "air-lock" seal to work. If there are gaps around the seal, you'll breathe thru the gaps because they are the "path of least resistance" in terms of airflow. Try this - cover the inlets gently and breathe in. If you have a good seal the mask should squash in to the facial skin a bit. Don't push down too hard because you'll break the face:mask seal.
3. How long have you been using the cartridge? Manufacturers usually say about 8 hours continuous use is the limit. If you use it intermittently, you'll get much less than that. The cartridge collects water vapor from the air and fills up. There's only so much space in the carbon bed in the cartridge - if it's filled with water, it won't collect solvent vapors. When in doubt, buy another.
4. Are you wearing protective gloves when you use the spirits? Organic solvents will go thru bare skin and cause fat removal, dermatitis, and you can also have some woozy head type symptoms - depends on what is in the "mineral spirits". And no - they ain't all the same chemically.
And finally,
5. I agree - ventilation! As in an open window, an open window and a fan, etc.
This is probably a lot more than you ever wanted to know about respirators, but - hey - you asked! And when you start to have symptoms - it's time to pay attention, brother. Please be careful! Hope this helps!
FYI - I take precautions myself. Respirator, gloves, open window - every time I sculpt with Magicsculpt or any 2 part epoxy that contains epichlorohydrin. Don't ever believe it when somebody says they can safely handle that stuff with bare hands. Look at the warnings on the products!
All the best,
Dan Morton,
ABIH Certified Industrial Hygienist